Serum hepcidin is significantly associated with iron absorption from food and supplemental sources in healthy young women13
نویسندگان
چکیده
Background: Hepcidin is a key regulator of iron homeostasis, but to date no studies have examined the effect of hepcidin on iron absorp-
منابع مشابه
Serum hepcidin is significantly associated with iron absorption from food and supplemental sources in healthy young women.
BACKGROUND Hepcidin is a key regulator of iron homeostasis, but to date no studies have examined the effect of hepcidin on iron absorption in humans. OBJECTIVE Our objective was to assess relations between both serum hepcidin and serum prohepcidin with nonheme-iron absorption in the presence and absence of food with the use of dual stable-iron-isotope techniques. DESIGN The study group incl...
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Background and Objective: Hepcidin is an acute-phase protein produced by the liver, which inhibits the proliferation of pathogens by increasing iron sequestration in macrophages and decreasing iron absorption. Although several studies have been performed on the role of hepcidin, data on its role in brucellosis are scarce. The aim of this study was to compare the serum level of hepcidin in patie...
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BACKGROUND Low iron absorption from important staple foods may contribute to iron deficiency in developing countries. To date, few studies have examined the iron bioavailability of pulse crops as commonly prepared and consumed by humans. OBJECTIVE The objectives were to characterize the iron absorption from a test meal of intrinsically labeled (57)Fe lentils prepared as dal, to compare the bi...
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Background and Objectives: Rheumatoid arthritis (RA) disease is a common inflammatory arthritis associated with joint destruction, motor disorder, and decreased life span. Hepcidin is an acute phase reactant protein which increases in inflammatory conditions mediated by IL-6 and its concentration elevates within the cell through regulating iron metabolism. The aim of this study was to evaluate ...
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Background: Prohepcidin, a liver-derived peptide with antimicrobial properties, is regulated by factors such as iron load and inflammation. Hepcidin is a central player in iron homeostasis. It downregulates the iron exporter ferroportin, thereby inhibiting iron absorption, release and recycling. Thus, prohepcidin increases the possibility of iron-limited erythropoiesis and development of anemia...
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